Searchable abstracts of presentations at key conferences in endocrinology

ea0035p617 | Female reproduction | ECE2014

Identification of elevated urine kisspeptin in pregnant women: a novel non-invasive biomarker of placental function?

Comninos Alexander , Jayasena Channa , Narayanaswamy Shakunthala , Abbara Ali , Nijher Gurjinder , Cheema Mansimran , Malik Zainab , Ghatei Mohammad , Bloom Stephen , Dhillo Waljit

Background: Kisspeptin is an RF amide peptide hormone critical for reproductive function. Kisspeptin is also abundantly expressed in the placenta, where it has an important physiological role in regulating placental invasion. Accordingly, plasma kisspeptin levels rise dramatically during normal pregnancy. Lower plasma levels of kisspeptin are associated with poor pregnancy outcomes such as recurrent miscarriage, intrauterine growth restriction and pre-eclampsia. Urinary measur...

ea0034p35 | Clinical biochemistry | SFEBES2014

Urinary kisspeptin as a novel marker of pregnancy

Comninos Alexander , Jayasena Channa , Narayanaswamy Shakunthala , Abbara Ali , Nijher Gurjinder , Cheema Mansimran , Malik Zainab , Ghatei Mohammad , Bloom Stephen , Dhillo Waljit

Background: Kisspeptin is an RF amide peptide hormone critical for reproductive function. Kisspeptin is also abundantly expressed in the placenta, where it has an important physiological role in regulating placental invasion. Accordingly, plasma kisspeptin levels rise dramatically during normal pregnancy. Lower plasma levels of kisspeptin are associated with poor pregnancy outcomes such as recurrent miscarriage, intrauterine growth restriction and pre-eclampsia. Urinary measur...